
1 2-Hexanediol MF: C6H14O2 MW: 118.17 A commonly used aliphatic diol, it possesses moisturizing, solubilizing, and stabilizing properties, finding extensive applications in cosmetics, industrial, and pharmaceutical fields.
| Item | Specification |
| Melting point | 45°C |
| Boiling point | 223-224°C (lit.) |
| Density | 0.951 g/mL at 25°C (lit.) |
| Vapor Density | 4.1 (vs air) |
| Vapor Pressure | 0.576 Pa at 25°C |
| Refractive Index | n20/D 1.442 (lit.) |
| Flash Point | >230°F |
| Specific rotation | [α]D₂₀ -0.3 to +0.3° (neat) |
| Acidity constant (pKa) | 14.49 ± 0.20 (Predicted) |
| Solubility | Freely soluble in water, ethanol, propylene glycol, and other polar solvents; slightly soluble in petroleum ether and other nonpolar solvents |
Cosmetics and Personal Care Sector
– Serves as a humectant, often paired with glycerin and hyaluronic acid.
– Aids in dissolving water-insoluble ingredients in formulations, such as certain actives (vitamins), plant extracts, or fragrances, enhancing product stability.
– Can synergize with other preservatives (e.g., phenoxyethanol) to reduce preservative dosage, making it suitable for sensitive skin products.
Common products: lotions, creams, serums, toners, masks, children’s skincare, etc.
Industrial Applications
– Serves as a solvent or film-forming aid in paints and inks, improving paint film flexibility and adhesion while regulating product viscosity.
– Added as a co-solvent in industrial cleaners for precision instruments or metal surface cleaning.
As a pharmaceutical excipient, it serves as a solubilizer and stabilizer in formulations such as oral liquids and ointments.
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