- Tianqiao District, Jinan City, Shandong Province, China
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Benzisothiazolinone (BIT) is a highly effective isothiazolinone compound with the mf： C₇H₅NOS 、 mw： 151.19. Its chemical structure consists of a fused benzene and thiazole ring, containing a ketone group (-C=O) and sulfur atom, which confer unique antimicrobial activity. Chemically stable, it is particularly suitable for alkaline environments. With broad-spectrum antimicrobial properties, high stability, and low toxicity, it is widely used in industrial, agricultural, and consumer goods sectors as a preservative, germicide, and antifungal agent.
| Item | Specification |
| Melting point | 154–158°C (lit.) |
| Boiling point | 204.5 ± 23.0 °C at 760 mmHg |
| Density | 1.4 ± 0.1 g/cm³ |
| Vapor pressure | 0.2 ± 0.4 mmHg at 25°C |
| Flash point | 77.5 ± 22.6 °C |
| Refractive Index | 1.745 |
| Acidity Constant (pKa) | 10.19±0.20 (Predicted) |
| Water Solubility | 1.288 g/L at 20°C |
| Solubility | Sparingly soluble in water; readily soluble in organic solvents such as dichloromethane, methanol, and DMSO; miscible with alcohols and surfactants in any proportion. |
Industrial Applications：
– Used as an in-can preservative for paints and inks to prevent mold growth and microbial contamination during storage.
– Employed for preserving polymers and adhesives such as acrylic emulsions and polyurethane dispersions.
– Applied as a preservative in metalworking fluids like cutting fluids and grinding fluids.
– Controls algae and biofilms in industrial circulating water and cooling systems.
Agricultural Applications：
– Serves as a fungicide against downy mildew in cucumbers, black spot in pears, and apple scab.
– Enhances seed germination rates and seedling survival through seed treatment.
Consumer Products：
– Added as a preservative in shampoos and skincare products.
– Used in leather and fabric treatments to prevent fungal decay.
– Incorporated into household cleaning products like detergents and spray cleaners.
Other Applications：
– Serves as a raw material for synthetic antimicrobial drugs, including certain antifungal and anticancer compounds.
– Added to marine coatings to inhibit algae and barnacle fouling.
Jinan Jinbang Chemical Co., Ltd., strategically located within the New Materials Industrial Park in Tianqiao District, Jinan City, Shandong Province, stands as a prominent chemical innovator since its establishment in 2015. Operating from a modern, expansive 37,500 m² manufacturing facility, we are dedicated to the research & development, production, and global distribution of high-performance chemical solutions.
We are always committed to delivering optimal chemical solutions for all application scenarios.
