
Chlorhydroxypyridine, MF: C7H7Cl2NO, MW: 192.04. Appearance: White or off-white powder. Stable under neutral and acidic conditions. No significant decomposition occurs when heated below 200°C. Hydrolysis occurs in strongly alkaline (pH > 12) and high-temperature (>300°C) environments, destroying the pyridine ring structure. The hydroxyl group (-OH) in its molecule can form complexes with metal ions, while the chlorine atom (-Cl) exhibits certain nucleophilic substitution reactivity.
| Item | Specification |
| Melting point | >320°C |
| Boiling point | 318.4±37.0°C at 760 mmHg |
| Density | 1.4±0.1 g/cm³ |
| Vapor pressure | 0.0±0.7 mmHg at 25°C |
| Refractive index | 1.578 |
| Flash point | 146.4±26.5 °C |
| Solubility | Extremely low solubility in water; slightly soluble in lower alcohols such as methanol and ethanol; soluble in alkaline solutions like dimethyl sulfoxide; insoluble in non-polar organic solvents. |
Specialized anticoccidial agent for poultry and livestock including chickens, rabbits, and turkeys, exhibiting inhibitory effects against multiple pathogenic coccidia such as Eimeria tenella, Eimeria necatrix, and Eimeria acervulina.
Serves as a model compound for studying the structure-activity relationships of pyridine-based heterocyclic drugs and for in vitro experiments on coccidian drug resistance mechanisms.
Functions as a precursor for synthesizing other pyridine derivatives (e.g., pesticide and pharmaceutical intermediates).
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