Dicyclohexylcarbodiimide

Cas 538-75-0

Dicyclohexylcarbodiimide Cas 538-75-0

Chemical Properties Of Dicyclohexylcarbodiimide Cas 538-75-0

Dicyclohexylcarbodiimide (DCC), MF: C₁₃H₂₂N₂ MW: 206.33, is an organic condensing agent belonging to the carbodiimide class. At room temperature, it is a white crystalline solid that decomposes readily upon contact with water and is highly hygroscopic. It is highly soluble in organic solvents and serves as a classic dehydrating condensing agent in organic and peptide synthesis, offering mild reaction conditions and high condensation efficiency.

Product Description Of Dicyclohexylcarbodiimide Cas 538-75-0

ItemSpecification
Melting Point132–135°C
Boiling Point122–124°C (6 mmHg)
Density0.977 g/cm³ (20°C)
Flash Point100°C
Refractive Indexn₂₀/D 1.485
SolubilityInsoluble in water; readily soluble in dichloromethane, DMF, THF, and aromatic hydrocarbons.

Product Application Of Dicyclohexylcarbodiimide Cas 538-75-0

  1. Organic Synthesis Condensation: Acts as a dehydrating condensing agent, catalyzing the reaction of carboxylic acids with amines and alcohols to efficiently synthesize amides, esters, and acid anhydrides under mild reaction conditions.
  2. Peptide Biochemical Synthesis: A specialized condensing agent for liquid-phase and solid-phase peptide synthesis that promotes the formation of peptide bonds between amino acids, thereby improving synthesis yields.
  3. Pharmaceutical intermediate synthesis: Dicyclohexylcarbodiimide is used for the condensation, ring-closing, and structural modification of drug molecules; a common synthetic auxiliary for active pharmaceutical ingredients (APIs) and pharmaceutical intermediates.
  4. Polymer materials: N N-dicyclohexylcarbodiimide is used in the synthesis of polyester and polyamide resins as a cross-linking curing agent to improve resin molding and heat resistance.
  5. Biochemical reagents: A dehydrating condensation reagent used in the synthesis of nucleic acids, nucleotides, and bioactive molecules.
Packaging Method Of Dicyclohexylcarbodiimide Cas 538-75-0
Product packaging bags
Bagged product shipping diagram 1
Cardboard barrel
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Jinan Jinbang Chemical Co., Ltd., strategically located within the New Materials Industrial Park in Tianqiao District, Jinan City, Shandong Province, stands as a prominent chemical innovator since its establishment in 2015. Operating from a modern, expansive 37,500 m² manufacturing facility, we are dedicated to the research & development, production, and global distribution of high-performance chemical solutions.

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