
Dicyclohexylcarbodiimide (DCC), MF: C₁₃H₂₂N₂ MW: 206.33, is an organic condensing agent belonging to the carbodiimide class. At room temperature, it is a white crystalline solid that decomposes readily upon contact with water and is highly hygroscopic. It is highly soluble in organic solvents and serves as a classic dehydrating condensing agent in organic and peptide synthesis, offering mild reaction conditions and high condensation efficiency.
| Item | Specification |
| Melting Point | 132–135°C |
| Boiling Point | 122–124°C (6 mmHg) |
| Density | 0.977 g/cm³ (20°C) |
| Flash Point | 100°C |
| Refractive Index | n₂₀/D 1.485 |
| Solubility | Insoluble in water; readily soluble in dichloromethane, DMF, THF, and aromatic hydrocarbons. |
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