
EDC HCl is a water-soluble carbodiimide organic compound MF: C₈H₁₇N₃·HCl, MW: 191.70, and serves as a zero-length crosslinker and carboxyl group activator. At room temperature and standard pressure, it is a white crystalline powder that is hygroscopic and readily soluble in water and polar organic solvents. As a key reagent in organic synthesis and biochemistry, it is widely used in peptide synthesis, protein cross-linking, drug preparation, and other fields.
| Item | Specification |
| Melting Point | 110–115°C (lit.) |
| Boiling Point | 209.2°C at 760 mmHg |
| Density | 0.877 g/mL (20°C, lit.) |
| Flash Point | 80.3°C |
| Vapor Pressure | 0.00661 mmHg (25°C) |
| Refractive Index | n20/D 1.461 |
| Solubility | Soluble in water (100 g/L), methanol, and ethanol; slightly soluble in diethyl ether and chloroform. |
| LogP | -2.98 (25°C) |
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