
Epicatechin (CAS: 490-46-0), also known as L-epicatechin, is a natural flavanol compound with the molecular formula C₁₅H₁₄O₆ and a molecular weight of 290.27. It is a stereoisomer of catechin, appearing as a white to pale yellow crystalline powder. It is widely found in tea leaves, cocoa, grape seeds, red wine, propolis, and various traditional Chinese medicinal herbs, and possesses strong antioxidant activity.
| Item | Specification |
| Melting Point | N/A |
| Boiling Point | N/A |
| Density | N/A |
| Isopotential Point (pI) | 8.75 |
| Optimal pH | 5.0–8.0 |
| Optimal Temperature | 55–65°C |
| Water Solubility | lightly soluble in water and glycerol; the aqueous solution is colorless to pale yellow |
| Active Sites | Cys25, His159, Asp158 |
| Stability | High heat resistance; does not lose activity completely at 90°C |
Health and Dietary Supplements: Epicatechin focuses on eliminating free radicals, anti-aging, and vascular protection, and is used in functional foods and dietary supplements designed to regulate blood lipids, protect the heart and brain, and combat fatigue.
Pharmaceutical and Research Sector: It possesses anti-inflammatory, antibacterial, hepatoprotective, and neuroprotective effects, making it suitable for related pharmaceutical research and development; it is also used in antioxidant testing and pharmacological experiments.
Personal Care and Skincare Sector: L-Epicatechin is used as an antioxidant and anti-aging ingredient in skincare products to improve dullness and signs of aging; it is also used in oral care products.
Food Industry Sector: As a natural food antioxidant, it inhibits oxidative browning of ingredients and extends shelf life.
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