Fluorescein Sodium

Cas 518-47-8

Fluorescein Sodium Cas 518-47-8

Fluorescein Sodium Cas 518-47-8

Chemical Properties Of Fluorescein Sodium Cas 518-47-8

  • Sodium fluorescein, also known as sodium fluorescein, disodium fluorescein, Acid Yellow 73, and Uranine, is the disodium salt of fluorescein. Its mf is C₂₀H₁₀Na₂O₅, and its mw is 376.27. It is a xanthene-type fluorescent dye belonging to the triarylmethane dye family.
  • Sodium fluorescein is an orange-red to deep red powder that is highly soluble in water; its aqueous solution exhibits yellow-green fluorescence, which is even stronger in alkaline media. As a fluorescent tracer, it features a small molecular radius (approximately 0.45 nm), which makes it highly effective in permeability studies.

Product Description Of Fluorescein Sodium Cas 518-47-8

Item Specification
Melting point 320°C
Boiling point 620.8°C at 760 mmHg
Density 0.579 [at 20°C]
Bulk density 600 kg/m³
Vapor pressure 2.133 hPa
Flash point 232.6°C
Color index 45350
Acid dissociation constants (pKa) 2.2, 4.4, 6.7 (at 25°C)
Maximum excitation wavelength 491 nm
Maximum emission wavelength 515 nm
Solubility Highly soluble in water (solubility approx. 500 g/L at 20°C), soluble in ethanol, slightly soluble in acetone, insoluble in diethyl ether and chloroform.
Stability Sensitive to light; decomposes easily under UV and blue light; stable at room temperature; store in a sealed container away from light.

Product Application Of Fluorescein Sodium Cas 518-47-8

  1. Medical Diagnostics:
    -Fluorescein Sodium is used for testing corneal injuries, ulcers, foreign bodies, and tear secretion, as well as for fundus fluorescein angiography (FFA) to diagnose retinal diseases
    -Serves as a diagnostic reagent for renal function and urinary tract patency; fluorescence can be detected in urine following intravenous injection;
    -Uranine is used in surgical procedures to identify the lymphatic system and the boundaries of tumor tissue;

  2. Biomedical Research:
    -Used in studies evaluating the permeability of the blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB)
    -Used for staining and tracing cells, chromosomes, and bacteria, and for studying cell migration and metabolism;
    -Used as a model to study drug distribution and pharmacokinetics

  3. Industrial and Environmental Applications:
    -Uranine is used for leak detection in piping systems, cooling systems, and seals, as well as a tracer to study water flow paths and residence times
    -Acid Yellow 73 is used for fluorescent whitening/marking of paper and textiles, as well as fluorescent labeling in sunscreen products and hair dyes

  4. Other Applications:
    Used for fluorescent microscopy of biological samples and as a fluorescent probe for developing pH and ion concentration sensors

Packaging Method Of Fluorescein Sodium Cas 518-47-8
Product packaging bags
Bagged product shipping diagram 1
Cardboard barrel
Factory Show

Jinan Jinbang Chemical Co., Ltd., strategically located within the New Materials Industrial Park in Tianqiao District, Jinan City, Shandong Province, stands as a prominent chemical innovator since its establishment in 2015. Operating from a modern, expansive 37,500 m² manufacturing facility, we are dedicated to the research & development, production, and global distribution of high-performance chemical solutions.

Factory Show
Factory Show
Factory Show
We Also Offer Other Hot Selling Products

Send Us A Message

We are always committed to delivering optimal chemical solutions for all application scenarios.