
Indole (MF: C8H7N, MW: 117.15) is an aromatic heterocyclic compound formed by the condensation of a benzene ring and a pyrrole ring. It occurs naturally in jasmine, citrus fruits, coal tar, and animal feces. At high concentrations, it has a distinctive odor; when highly diluted, it possesses a jasmine-like fragrance. It is an extremely important basic organic synthesis intermediate in the chemical, fragrance, and pharmaceutical industries.
| Item | Specification |
| Melting point | 51–54 °C (lit.) |
| Boiling point | 253–254 °C (lit.) |
| Bulk density | 230 kg/m³ |
| Density | 1.22 g/cm³ |
| Vapor pressure | 0.016 hPa (25°C) |
| Refractive index | 1.681 |
| Flash point | 107.8–135°C |
| Freezing point | >51°C |
| Acid dissociation constant (pKa) | 3.17 (quoted, Sangster, 1989) |
| Odor | Fecal odor; floral scent when highly diluted |
| Solubility | Sparingly soluble in water; readily soluble in organic solvents such as ethanol, diethyl ether, benzene, and toluene. |
| Acid-base properties | Weakly acidic; forms salts with strong bases. |
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