
Isophthaloyl dichloride is a crucial organic synthesis intermediate with the mf:C₈H₄Cl₂O₂ and mw: 203.02. The acyl chloride functional group (-COCl) in its molecular structure is a strong electrophile, readily undergoing substitution reactions with compounds containing active hydrogen. Industrially, it is primarily synthesized by reacting isophthalic acid with chlorinating agents such as phosphorus trichloride, phosphorus pentachloride, or phosgene.
| Item | Specification |
| Melting point | 43–44 °C (lit.) |
| Boiling point | 276 °C (lit.) |
| Density | 1.42 g/cm³ |
| Vapor Pressure | 0.03 mm Hg (25 °C) |
| Refractive Index | 1.5700 |
| Flash point | 356 °F |
| Solubility | Insoluble in water; readily soluble in organic solvents such as benzene, toluene, xylene, chloroform, etc. |
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