
Isosorbide Dimethyl Ether (DMI) is a green, multifunctional solvent and additive derived from renewable resources. Molecular Formula: C8H14O4, MW: 174.2. It exhibits excellent stability, remaining stable at room temperature against acids and alkalis (pH range 3-11) without undergoing hydrolysis, oxidation, or decomposition reactions. Its low reactivity prevents chemical interactions with most active ingredients, enabling stable formulation compatibility. It is gradually biodegradable by microorganisms in soil and aquatic environments. Widely used in pharmaceuticals, cosmetics, and fine chemicals, it serves as an important eco-friendly alternative to traditional highly toxic solvents.
| Item | Specification |
| Melting point | -70°C |
| Boiling point | 93-95°C at 0.1 mmHg (lit.) |
| Density | 1.15 g/mL at 25°C (lit.) |
| Vapour pressure | 12.54 Pa at 20°C |
| Refractive index | n20/D 1.461 (lit.) |
| Flash Point | 227°F |
| PH | 7.0–8.0 (100 g/L, H₂O, 20°C) |
| Optical rotation | [α]₂₁/D +96.1°, c = 2% in chloroform |
| Viscosity | 3.5–4.5 mPa·s at 20°C |
| Solubility | Completely miscible with water; also dissolves alcohols, ethers, esters, vegetable oils, most organic small molecules, and certain polymers. |
Pharmaceutical Applications – High-Safety Solvent and Solubilizing Agent:
– Drug Solvent: Enhances solubility for poorly soluble APIs in oral formulations or injections.
– Transdermal Absorption Enhancer: Added to patches and gels to boost drug penetration without skin irritation.
– Pharmaceutical intermediate synthesis: Serves as an eco-friendly reaction solvent, replacing DMF and DMSO in heterocyclic compound synthesis.
Cosmetics and Personal Care – Mild Solvent and Moisturizer:
– Solvent and stabilizer: Stabilizes formulations in serums, lotions, lipsticks, etc., suitable for sensitive skin and infant skincare products.
– Moisturizer: Offers superior hydration to glycerin without stickiness, improving product feel.
– Sunscreen Solubilizer: Added to sunscreens to dissolve insoluble physical or chemical sunscreens, preventing particle agglomeration.
Industrial and Fine Chemicals Sector – Eco-friendly solvents and process aids:
– Precision cleaning solvents: Used for cleaning electronic components and optical lenses, meeting the electronics industry’s “halogen-free and eco-friendly” requirements.
– Coatings and ink solvents: Used in water-based coatings and UV-curable inks.
– Polymer processing aids: Function as plasticizers or antistatic agents for plastics and fibers.
Agricultural Sector, Pesticide Synergist Additives:
– Pesticide solvents and penetrants: Formulated into emulsifiable concentrates or suspension concentrates for herbicides and insecticides.
– Bio-stimulant carriers: Serve as dissolution carriers for bio-stimulants like humic acids and amino acids in liquid fertilizer production.
Jinan Jinbang Chemical Co., Ltd., strategically located within the New Materials Industrial Park in Tianqiao District, Jinan City, Shandong Province, stands as a prominent chemical innovator since its establishment in 2015. Operating from a modern, expansive 37,500 m² manufacturing facility, we are dedicated to the research & development, production, and global distribution of high-performance chemical solutions.
We are always committed to delivering optimal chemical solutions for all application scenarios.