
| Item | Specification |
| Melting point | ~169°C (dec.) |
| Boiling point | 397.76°C (rough estimate) |
| Density | 1.32 g/cm³ |
| Specific rotation | -47° (C=5, H₂O, 12 HR) |
| Refractive index | 1.45–1.47 |
| Flash point | 365.4 ± 31.5 °C |
| Solubility | Soluble in water, slightly soluble in methanol, practically insoluble in toluene. |
| Acidity coefficient (pKa) | 11.67 ± 0.20 (Predicted) |
| Optical rotation | [α]20/D 48 ± 2°, 24 hr, c = 1% in H₂O |
Lactulose is primarily used in medicine as an osmotic laxative and a drug to reduce blood ammonia levels. It has mature and widespread clinical applications, including: Treatment of constipation and hepatic encephalopathy. It is also used for preoperative intestinal preparation and the treatment of functional bloating, etc.
Due to its ‘prebiotic properties’ and ‘low calorie content,’ lactulose has been approved by some countries and regions as a food additive or functional ingredient, with primary applications including:
Prebiotic supplements, which promote the proliferation of beneficial gut bacteria and regulate gut microbiota, suitable for individuals seeking to improve gut health.
As a low-calorie sweetener, lactulose can be used in sugar-free foods, low-sugar beverages, and health foods (such as those suitable for diabetic patients), satisfying sweetness needs while controlling calorie intake.
A small amount of lactulose is added to some infant formula to help regulate intestinal function in infants and prevent constipation.
In the livestock industry, lactulose is primarily used to improve intestinal health in livestock and poultry, prevent constipation; promote growth, regulate intestinal microbiota, enhance feed digestion and absorption rates, and boost immunity.
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