
Valerophenone (MF: C₁₁H₁₄O, MW: 162.23) is a crucial organic synthesis intermediate featuring a benzene ring and a pentyl side chain. The carbonyl group (C=O) in its molecule serves as a characteristic functional group, enabling reactions such as ketone reduction, oxidation, and addition. The ketone group (C=O) in its molecule can undergo addition reactions with Grignard reagents, amines, alcohols, etc., yielding derivatives such as alcohols, imines, and ketals.
| Item | Specification |
| Melting point | -9°C |
| Boiling point | 244-245°C (lit.) |
| Density | 0.975 g/mL at 20°C (lit.) |
| Odor | Herbaceous |
| Refractive index | n20/D 1.5143 (lit.) |
| Flash point | 217°F |
| Specific gravity | 0.98 |
| Solubility | Insoluble in water; soluble in ethanol, acetone, diethyl ether, chloroform (slightly soluble), ethyl acetate (slightly soluble). |
As an intermediate, Valerophenone is used in pharmaceutical synthesis, such as antidepressants, analgesics, antiepileptic drugs, and other fine chemical products.
As a fragrance ingredient, it is used in cosmetic fragrances (perfumes, cosmetics, detergents) and food flavorings (baked goods, confectionery, beverages).
Other applications:
– As a solvent in resins, paints, cleaners, and degreasers
– As a modifier in inks, adhesives, resins, and coatings to enhance viscosity, flow, and chemical resistance
– As a cosmetic ingredient in lipsticks, skin creams, etc.
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