


Ethyl acetoacetate (abbreviated as EAA) is an important β-diketone compound with the mf C₆H₁₀O₃ and mw 130.14. It is produced from ethyl acetate via the Claisen ester condensation reaction. At standard temperature and pressure, it exists as a colorless or pale yellow transparent liquid with a sweet, fruity aroma (resembling honey or caramel). The core characteristic of ethyl acetoacetate is its enol-keto tautomerism – enol tautomerism, endowing it with multiple structural properties of ketones, esters, and enols, making it chemically reactive.
| Item | Specification |
| Melting point | −43°C (lit.) |
| Boiling point | 181°C (lit.) |
| Density | 1.029 g/mL at 20°C (lit.) |
| Vapor Density | 4.48 (vs air) |
| Vapor Pressure | 1 mmHg (28.5°C) |
| Refractive Index | 1.419–1.421 (20°C) |
| Flash Point | 185°F |
| APHA | ≤15 |
| Viscosity | 0.45 mPa·s (at 20°C) |
| APHA | ≤15 |
| Acidity coefficient (pKa) | 11 (at 25°C) |
| Specific gravity | 1.027–1.035 (20/4°C) |
| Relative Polarity | 0.577 |
| Autoignition Temperature | ~370°C |
| Viscosity | 1.58 mPa·s (20°C) |
| Odor Threshold | ~0.1 ppm |
| Solubility | Sparingly soluble in water; readily soluble in organic solvents such as alcohols, ethers, benzene, acetone. |
Ethyl acetoacetate serves as a key raw material for synthesizing ketones, carboxylic acids, esters, and heterocyclic compounds;
Ethyl acetoacetate functions as a critical intermediate in synthesizing anti-tuberculosis drugs, antipyretic analgesics, and vitamins B₁/B₆;
Used as an intermediate in synthesizing herbicides, insecticides, and fungicides; also employed in synthesizing plant growth regulators.
Acetoacetic ester serves as an intermediate for synthesizing azo dyes, acid dyes, and reactive dyes, and is used in preparing fluorescent pigments and organic pigments.
As a fragrance intermediate, acetoacetic ester synthesizes floral and fruity aromas for blending food flavorings or cosmetic products.
Acetoacetic ester serves as a specialty solvent, metal extractant, polymerization monomer, or crosslinking agent. Ethyl acetoacetate
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