- Tianqiao District, Jinan City, Shandong Province, China
- export01@jinbangch.com
- Mon to Sun: 8:00am – 6:00pm
Methyl acetoacetate is a versatile, highly reactive β-keto ester intermediate with the mf C₅H₈O₃ and mw 116.12. It is typically synthesized from methyl acetate via the Claisen condensation reaction (catalyzed by sodium alcoholates, sodium amides, etc.). At standard temperature and pressure, it exists as a colorless, transparent liquid with a mild fruity aroma (resembling apple or honey). At high purity, it readily undergoes slight keto-enol tautomerism, exhibiting both solvent properties and reactant characteristics.
| Item | Specification |
| Melting point | -80°C (lit.) |
| Boiling point | 169-170°C/70 mmHg (lit.) |
| Density | 1.076 g/mL at 25°C (lit.) |
| Vapor Density | 4 (vs air) |
| Vapor Pressure | 1 hPa (20°C) |
| Refractive Index | 1.418–1.420 (20°C) |
| Flash Point | 67°C |
| APHA | ≤20 |
| Viscosity | 0.45 mPa·s (at 20°C) |
| APHA | ≤15 |
| Acidity coefficient (pKa) | 10.67 ± 0.46 |
| Odor | Fresh citrus scent |
| Viscosity | 1.5 mPa·s (20°C) |
| Solubility | Sparingly soluble in water; readily soluble in organic solvents such as alcohols, ethers, ketones, benzene, and petroleum ether. |
As an organic synthesis intermediate, Methyl acetoacetate is used to synthesize important organic compounds such as β-amino acids, β-hydroxy acids, keto acid esters, and heterocyclic compounds;
In the pharmaceutical field, Methyl acetoacetate is a key intermediate for synthesizing Vitamin B1 and is also used in the preparation of anti-epileptic drugs, antibacterial/antihypertensive drugs, etc.;
In agriculture, it synthesizes herbicides and prepares insecticides and fungicides;
It synthesizes azo dyes, prepares fluorescent pigments, and serves as a modifier for dye intermediates;
As a food flavoring, Acetoacetic Acid Methyl Ester blends fruit aromas like apple, banana, and strawberry;
As a film-forming aid in solvent-based coatings, Acetoacetic Acid Methyl Ester is used in paints and adhesives. It also serves as an intermediate plasticizer for polyvinyl chloride (PVC) and as a standard substance for chromatographic analysis.
Jinan Jinbang Chemical Co., Ltd., strategically located within the New Materials Industrial Park in Tianqiao District, Jinan City, Shandong Province, stands as a prominent chemical innovator since its establishment in 2015. Operating from a modern, expansive 37,500 m² manufacturing facility, we are dedicated to the research & development, production, and global distribution of high-performance chemical solutions.
We are always committed to delivering optimal chemical solutions for all application scenarios.
